A tetraester derivative of fluorescent calix[4]arene bearing a proton-ionizable moiety for highly sensitive extraction-fluorometric determination of sodium ion

作者：Nakahara Yoshio^*; Furuno Yuta; Iwamoto Hitoshi; Yajima Setsuko; Kimura Keiichi

来源：Supramolecular Chemistry, 2018, 30(8): 697-705.

DOI：10.1080/10610278.2018.1447110

• Tetraester derivative of calix[4]arene
• p-nitrophenol moiety
• sodium ion
• extraction-fluorometric detection
• flow injection analysis

In this study, we report the highly sensitive extraction-fluorometric detection system of Na+ using flow injection analysis with a tetraester derivative of fluorescent calix[4]arene. In liquid-liquid extraction experiments, the fluorescent intensity of calix[4]arene derivative 1 bearing a p-nitrophenol moiety was highly dependent on pH and the Na+ concentration in the aqueous phase. On the other hand, such phenomenon was not observed in the case of calix[4]arene derivative 2, which is almost the same structure as 1 except for a p-nitrophenol moiety. These results show that the proton dissociation of the p-nitrophenol moiety decisively affects the fluorescence intensity of 1. Owing to these fluorescence responsiveness, a calibration graph of the Na+ concentration could be successfully prepared using flow injection analysis with good linearity at the tens of nanomolar level. The tetraester scaffold of calix[4]arene was essential to the detection of Na+ in such a very low concentration range.
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• 出版日期2018