Postsynaptic depolarization requirements for LTP and LTD: a critique of spike timing-dependent plasticity

作者：Lisman J^*; Spruston N

来源：Nature Neuroscience, 2005, 8(7): 839-841.

DOI：10.1038/nn0705-839

Long-term potentiation and long-term depression require postsynaptic depolarization, which many current models attribute to backpropagating action potentials. New experimental work suggests, however, that other mechanisms can lead to dendritic depolarization, and that backpropagating action potentials may be neither necessary nor sufficient for synaptic plasticity in vivo.

• 出版日期2005-7
• 单位西北大学