An outbreak of duck hepatitis A virus type 1 infection in Japan

作者：Kamomae Masahiro; Kameyama Mamoru; Ishii Jun; Nabe Mikoto; Ogura Yuji; Iseki Hiroshi; Yamamoto Yu; Mase Masaji^*

来源：Journal of Veterinary Medical Science, 2017, 79(5): 917-920.

DOI：10.1292/jvms.16-0646

• DHAV-1
• hepatitis
• RT-PCR

In June 2015, a highly fatal and acute disease broke out in a duckling farm in Hyogo Prefecture, Japan. The birds exhibited poor growth, reduced movement, lying in a dorsal recumbent position, depression, lethargy, ataxia and opisthotonus, with a high mortality rate of approximately 76%. By performing a reverse transcription-polymerase chain reaction (RT-PCR) using primers specific for duck hepatitis A virus type 1 (DHAV-1), we obtained the PCR products of a predicted size. The nucleotide sequences of the PCR products showed a > 96% identity with that of the DHAV-1, HB02 strain, which was isolated in China. To our knowledge, this is the first time that the DHAV-1 virus has been isolated since its outbreak in Japan in 1963.

• 出版日期2017-5