A two-directional approach to pyrrolizidines: total syntheses and biological evaluation of alkaloid cis-223B and (+/-)-xenovenine

作者:Barthelme Alexandre*; Richards David; Mellor Ian R; Stockman Robert A
来源:Chemical Communications, 2013, 49(89): 10507-10509.
DOI:10.1039/c3cc46800c

摘要

Total syntheses of alkaloid cis-223B and xenovenine are reported in 3 and 4 steps respectively using a two-directional synthesis/triple reductive amination strategy, and their neurotoxic properties assessed.

  • 出版日期2013