The Status of Maculopathy in Diabetes and Prediabetes Patients in a Population-Based Study Detected by Optical Coherence Tomography: The 2011 Health Examination Survey in Beijing

作者：Cao, Xi; Xin, Zhong; Li, Shiming; Qi, Yue; Yuan, Mingxia; Zhu, Xiaorong; Yang, Jin-Kui^*

来源：Biomed Research International, 2017, 2017: 6513076.

DOI：10.1155/2017/6513076

• MACULAR EDEMA
• RETINAL THICKNESS
• RISK-FACTORS
• RETINOPATHY
• PREVALENCE
• DEGENERATION
• ASSOCIATION
• PROGRESSION
• MELLITUS
• TYPE-2

Objective. The aim of the study was to investigate the prevalence and the risk factors of maculopathy detected by optical coherence tomography (OCT) in a Chinese population with diabetes or prediabetes. Methods. 8,155 people were randomly selected to participate in the 2011 annual Health Examination Survey in Beijing. A 75 g oral glucose tolerance test (OGTT) was tested in 3760 subjects with fasting plasma glucose (FPG) >= 5.6mmol/L. Of 3,760 subjects, 583 were also randomly selected to take OCT. Results. In this study population, 21 (3.95%) patients had maculopathy. Eight patients had diabetes macular edema (DME) and the prevalence was 6.72% in diabetes patients and 1.51% in all subjects. Eleven patients had age-related macular degeneration (AMD) and the prevalence was 3.36% in diabetes patients and 2.07% in all subjects. Logistic regression model confirmed that elevated HbA1c (p < 0.001) and systolic pressure (p < 0.05) made significant contributions to DME. Stepwise regression analysis revealed that HbA1c and blood creatinine were significantly independent influence factors for central subfield thickness (CST) (p = 0.01, p < 0.001). Conclusions. High prevalence of maculopathy was found in patients with diabetes in a Chinese population. Maculopathy poses a significant public health problem in China with rapid rising trend of diabetes.

• 出版日期2017
• 单位首都医科大学