A new approach for risk assessment of aggregate dermal exposure to banned azo dyes in textiles

作者：Chen, Xuezhang^*; Deng, Qixi; Lin, Shubao; Du, Chao; Zhao, Shengqiao; Hu, Yongjie; Yang, Zhongguo; Lyu, Yanhui; Han, Jianjian

来源：Regulatory Toxicology and Pharmacology, 2017, 91: 173-178.

DOI：10.1016/j.yrtph.2017.10.022

• Azo dyes
• Textile
• Aromatic amines
• Risk assessment

A semi-quantitative risk assessment of banned azo dyes in textiles was performed to assess the health risk when consumers have direct dermal contact with these products. A novel model, which includes three exposure scenarios, was proposed to estimate the absorption of leachable azo dyes from twenty textiles samples. The effective daily uptakes of benzidine from sample 1 and sample 19 in chronic exposure model were 0.318 ng/kg-day and 0.011 ng/kg-day, respectively. Compared to virtually safe dose (VSD), the corresponding cancer risks were 7.42 x 10(-5) (Sample 1) and 2.56 x 10(-6) (Sample 19). As noted by nomograph assessment, the health risk induced by long-term exposure of banned azo dyes from textiles was at the range of "very low" to "low". In short-term exposure cases, the risks were acceptable though the amount of defected aromatic amines was relatively high in particular samples. The amount of exposure and the risk level might be overestimated as a series of assumptions were made under extreme conditions.

• 出版日期2017-12
• 单位广东产品质量监督检验研究院; 广东省标准化研究院