Discrimination of squamous cell carcinoma in situ from seborrheic keratosis by color analysis techniques requires information from scale, scale-crust and surrounding areas in dermoscopy images

作者：Shakya N M; LeAnder R W^*; Hinton K A; Stricklin S M; Rader R K; Hagerty J; Stoecker W V

来源：Computers in Biology and Medicine, 2012, 42(12): 1165-1169.

DOI：10.1016/j.compbiomed.2012.09.010

• Squamous cell carcinoma
• Seborrheic keratosis
• Image processing
• Scale
• Crust
• Dermoscopy
• Bowen's disease

Scale-crust, also termed "keratin crust", appears as yellowish-to-tan scale on the skin's surface. It is caused by hyperkeratosis and parakeratosis in inflamed areas of squamous cell carcinoma in situ (SCCIS, Bowen's disease) and is a critical dermoscopy feature for detecting this skin cancer. In contrast, scale appears as a white-to-ivory detaching layer of the skin, without crust, and is most commonly seen in benign lesions such as seborrheic keratoses (SK). Distinguishing scale-crust from ordinary scale in digital dermoscopy images holds promise for early SCCIS detection and differentiation from SK. Reported here are image analysis techniques that best characterize scale-crust in SCCIS and scale in SK, thereby allowing accurate separation of these two dermoscopic features. Classification using a logistic regression operating on color features extracted from these digital dermoscopy structures can reliably separate SCCIS from SK.

• 出版日期2012-12-1