摘要

The enantioselective domino Michael/Henry reaction of nitroalkenes with succinaldehyde was found to proceed efficiently upon using diphenylprolinol silyl ether as the organocatalyst. The reaction affords cis-disubstituted nitropen-tenes with excellent diastereoselectivities and enantioselectivities after treatment of the Michael product with Ac2O and pyridine.

  • 出版日期2015-7