An investigatory study of antibacterial activity of functionalized spirooxindoles

作者:Kidwai Mazaahir*; Jain Arti; Singh Satendra; Nemaysh Vishal; Luthra Pratibha Mehta
来源:Indian Journal of Chemistry - Section B: Organic and Medicinal Chemistry , 2014, 53(4): 399-411.

摘要

Synthesis of functionalized spirooxindoles have been reviewed and it has been proposed that the unique core ring system that is common to this family of compounds arises by a biological Knoevengal-Michael-Domino cyclization along with the attachment of hydrophobic alkyl chain linkage. These newly synthesized compounds have been also tested for their in vitro antibacterial activities against some bacterial strains viz. Staphylococcus aureus, Staphylococcus epidermidis, Escherichia coli and Pseudomonas aeruginosa.

  • 出版日期2014-4