Anti-contamination device for cryogenic soft X-ray diffraction microscopy

作者：Huang Xiaojing^*; Miao Huijie; Nelson Johanna; Turner Joshua; Steinbrener Jan; Shapiro David; Kirz Janos; Jacobsen Chris

来源：Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment , 2011, 638(1): 171-175.

DOI：10.1016/j.nima.2011.02.085

• X-ray Imaging
• Cryogenic X-ray microscopy
• Diffraction microscopy
• Anti-contamination

Cryogenic microscopy allows one to view frozen hydrated biological and soft matter specimens with good structural preservation and a high degree of stability against radiation damage. We describe a liquid nitrogen-cooled anti-contamination device for cryogenic X-ray diffraction microscopy. The anti-contaminator greatly reduces the buildup of ice layers on the specimen due to condensation of residual water vapor in the experimental vacuum chamber. We show by coherent X-ray diffraction measurements that this leads to fivefold reduction of background scattering, which is important for far-field X-ray diffraction microscopy of biological specimens. Published by Elsevier B.V.

• 出版日期2011-5-11
• 单位西北大学