科研之友
微信
新浪微博
Facebook
分享链接
摘要
Mycophenolate mofetil (MMF) is an immunosupressor agent frequently used in patients after bone marrow or solid organ transplants. The most common adverse reactions of the drug are gastrointestinal, specially diarrhea and vomiting. We report a 53-year-old male, that received a heart transplant receiving immunosuppression cyclosporine, mycophenolate mofetil and prednisone. Six months after the transplant, the patient started with diarrhea, anorexia and weight loss. A duodenal biopsy showed vinous atrophy Celiac disease and the presence of parasites were discarded. Mycophenolate mofetil was discontinued and one week later diarrhea subsided. Two months later the patient was asymptomatic and recovered weight. A new duodenal biopsy showed absence of villous atrophy (Rev Med Chile 2010; 138: 590-594).
- 出版日期2010-5
