Development of Novel Protease Assay Device Using a Nanoimprinted Two-dimensional Photonic Crystal

作者:Hashimoto Wakana; Endo Tatsuro*; Sueyoshi Kenji; Hisamoto Hideaki
来源:Chemistry Letters, 2014, 43(11): 1728-1730.
DOI:10.1246/cl.140674

摘要

We developed a novel protease assay device using nano-imprinted two-dimensional photonic crystal (2D-PhC) for the first time. 2D-PhC exhibits a characteristic reflection, and its intensity is strongly affected by small changes in refractive index (RI) of the 2D-PhC surface. In this study, protease substrate-immobilized 2D-PhC was newly developed in order to measure the protease activity, and the simple and selective detection of protease activity using 2D-PhC was successfully performed.

  • 出版日期2014-11-5