Antimicrobial, herbicidal and antifeedant activities of mansonone E from the heartwoods of Mansonia gagei Drumm.

作者：Mongkol Rachsawan; Chavasiri Warinthorn^*

来源：Journal of Integrative Agriculture, 2016, 15(12): 2795-2802.

DOI：10.1016/S2095-3119(16)61444-2

• Mansonia gagei Drumm.
• mansonone E
• plant pathogens
• antifungal
• antibacterial
• antifeedant
• herbicidal activities

In vitro biological activities including anti-phytopathogenic fungi, antibacterial, antifeedant and herbicidal activities of the extracts from the heartwoods of Mansonia gagei Drumm. were evaluated. The dichloromethane (DCM) extract displayed antifungal activity against four plant pathogenic fungi (Altemaria porri, Colletotrichum gloeosporioides, Fusarium oxysporum and Phytophthora parasitica) higher than the methanolic (MeOH) extract. The separation of the DCM extract using bioassay guided antifungal activity against P. parasitica led to the isolation of nnansorins A, B, and C, mansonones C, E, G and H. Among isolated compounds, mansonone E displayed the highest antifungal activity against P parasitica, followed by mansonone C, nnansorin B and mansonone G. This potent compound revealed the same minimum inhibitory concentrations (MIC) of 31 mu g mL(-1) against C. gloeosporioides and P. parasitica, and minimum fungicidal concentration (MFC) of 31 and 125 mu g mL(-1), respectively. Moreover, mansonone E exhibited highly significant antibacterial activity against both Xanthomonas otyzae pv. otyzae (Xoo) and X. otyzae pv. oryzicola.(Xoc) with MIC and minimum bactericidal concentration (MBC) as 7.8 and >500 mu g mL(-1), respectively. This compound furthermore could inhibit the feed of Spodoptera litura with 45.9% antifeedant and significantly herbicidal activity reduced the shoot and root growth of Brassica chinensis, Otyza sativa, Mimosa pigra and Echinochlooa crus-galli. Mansonone E has potential as a new natural pesticide for agricultural plant pathogen management.

• 出版日期2016