Ni-Al2O3 as reusable heterogeneous catalyst for expedient one-pot synthesis of naphthopyrans

作者：Kalita Subarna Jyoti; Saikia Nilakhy; Deka Dibakar Chandra^*; Mecadon Hormi^*

来源：Research on Chemical Intermediates, 2016, 42(9): 6863-6871.

DOI：10.1007/s11164-016-2500-4

• Ni-Al2O3
• Chromenes
• One-pot
• Three-component reaction

Ni-Al2O3 is an efficient and reusable heterogeneous catalyst for the synthesis of naphthopyrans by one-pot three-component reaction of naphthols, aldehydes, and malononitrile in EtOH/H2O (1:1) solvent medium. A comparative study of Ni-Al2O3 with neutral Al2O3 revealed that reactions with the former afforded better product yields, indicating higher catalytic efficacy. Ni-Al2O3 due to its low cost, good activity, ease of handling, and easy recovery, with high yields and simple purification method makes the procedure highly applicable.
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• 出版日期2016-9