A Cobalt Nitrate/Hydrogen Peroxide System as an Efficient Reagent for the Synthesis of 2-Aryl Benzimidazoles and Benzothiazoles

作者：Chandrachood Pranav S; Garud Dinesh R; Gadakari Tushar V; Torane Rasika C; Deshpande Nirmala R; Kashalkar Rajashree V^*

来源：Acta Chimica Slovenica, 2011, 58(2): 367-371.

• o-phenylenediamine
• o-aminothiophenol
• aldehyde
• cobalt nitrate hexahydrate
• hydrogen peroxide

Benzimidazoles and benzothiazoles show significant and promising activities against various viruses such as HIV and HCMV-1. Their synthesis using cobalt nitrate and hydrogen peroxide in N,N-dimethylformamide has been presented in the following study. The cobalt nitrate/H(2)O(2) appears to be a smooth and efficient reagent system for the synthesis of 2-aryl substituted benzimidazoles and benzothiazoles. Simple and convenient reaction procedures and shorter reaction times are the salient features of the presented route.

• 出版日期2011