A survey of synthetic nicotinamide cofactors in enzymatic processes

作者：Paul Caroline E^*; Hollmann Frank

来源：Applied Microbiology and Biotechnology, 2016, 100(11): 4773-4778.

DOI：10.1007/s00253-016-7500-1

• Biocatalysis
• Biomimetics
• Cofactor analogues
• mNADHs
• Synthetic nicotinamide cofactors
• Oxidoreductases

Synthetic nicotinamide cofactors are analogues of the natural cofactors used by oxidoreductases as redox intermediates. Their ability to be fine-tuned makes these biomimetics an attractive alternative to the natural cofactors in terms of stability, reactivity, and cost. The following mini-review focuses on the current state of the art of those biomimetics in enzymatic processes.

• 出版日期2016-6