An alternative way to think about glaucoma screening, using a questionnaire as a tool, Chinese version

作者：Kuo, Li Lin; Tsai, Ching Yao; Hsiao, Ya Chuan; Chou, Pesus^*

来源：Journal of Evaluation in Clinical Practice, 2012, 18(4): 816-821.

DOI：10.1111/j.1365-2753.2011.01683.x

• glaucoma
• questionnaire
• screening test

Rationale, aims and objectives To develop a short screening test for the detection of preclinical glaucoma. Method This casecontrol study involved 690 participants aged 40 years or older: 338 patients with glaucoma or suspected glaucoma and 352 patients without glaucoma, who served as a control group. All participants were interviewed by a single trained research assistant. Patients' basic demographic and clinical information, past ophthalmic history and responses on the National Eye Institute 25-item Visual Function Questionnaire were collected. Two glaucoma-trained ophthalmologists examined all the participants using standard procedures to make a diagnosis. The biostatistical differences between the two groups were determined. Results Five items were selected for glaucoma screening: Sense of worse vision compared with those of the same age, Ocular pain or discomfort during the past 6 months, History of cataract, Family history of glaucoma and Hyperopia. A score of 2 or more was used to define a group of positive cases with the most appropriate values for sensitivity (79.0%), specificity (76.7%) and predictive power (a positive predictive value of 76.5% and a negative predictive value of 79.2%). Conclusion A five-item instrument was developed to detect preclinical glaucoma. Anyone with a score of 2 or more may need further ophthalmic examination and treatment.

• 出版日期2012-8