Nasopharyngeal endoscopic resection in the management of selected malignancies: ten-year experience

作者：Castelnuovo P; Dallan I^*; Bignami M; Battaglia P; Mauri S; Villaret A Bolzoni; Bizzoni A; Tomenzoli D; Nicolai P

来源：Rhinology, 2010, 48(1): 84-89.

DOI：10.4193/Rhin09.079

• endoscopic surgery
• recurrence
• nasopharynx
• nasopharyngeal cancer
• nasopharyngectomy

Objective: To evaluate the feasibility of endoscopic surgery in the management of selected nasopharyngeal cancers. Three different types of nasopharyngeal endoscopic resections (NER) are described.
Method of study: From January 1997 to October 2008, 17 consecutive patients (mean age: 50 years) with previously untreated (5) or recurrent nasopharyngeal tumours (12) were treated with curative intent by pure endoscopic resection. The extent of surgical resection was classified as follows: type 1 NER: resection limited to the postero-superior nasopharyngeal wall; type 2 NER: resection superiorly extended to the sphenoid sinus; type 3 NER: resection with lateral extension including the cartilaginous portion of the Eustachian tube and parapharyngeal space.
Results: Type 1 NER was performed in 4 cases, type 2 in 6, and type 3 in 7. No intra- or postoperative complications were observed. Mean hospitalization time was 4 days (range: 1-7). Follow-up ranged from 10 to 138 months (mean: 41,2 38). At the time of writing, 12 (71%) patients were free of disease, 3 (17%) alive with disease, and 2 (12%) dead of disease.
Conclusions: NER is a feasible surgical technique that can be tailored in relation to tumour extension. Larger series and longer follow-up are needed to further validate the long-term results.

• 出版日期2010-3