Addition of titanium ester enolates to aldimines containing a chiral alpha-methylbenzylamine moiety: synthesis of chiral syn-beta-amino esters

作者：Periasamy Mariappan^*; Suresh Surisetti; Ganesan Subramaniapillai Selva

来源：Tetrahedron: Asymmetry , 2006, 17(9): 1323-1331.

DOI：10.1016/j.tetasy.2006.04.032

Addition of titanium ester enolates to N-arylidene derivatives containing a (R)-alpha-methylbenzylamine moiety afforded (2S,3S,alpha R)-beta-amino esters in 73-93% yields with 86:14 to 96:4 diastereomeric ratios.

• 出版日期2006-5-15