Allylamine and Allyl Alcohol Plasma Copolymerization: Synthesis of Customizable Biologically-Reactive Three-Dimensional Scaffolds

作者：Hawker Morgan J; Pegalajar Jurado Adoracion; Hicks Kiah I; Shearer Jeffrey C; Fisher Ellen R

来源：Plasma Processes and Polymers, 2015, 12(12): 1435-1450.

DOI：10.1002/ppap.201500098

• allylamine
• biomaterials
• plasma polymerization
• surface modification
• three-dimensional materials

Plasma copolymerization is a powerful plasma-enhanced chemical vapor deposition (PECVD)-based technique, and offers a distinct advantage over single-precursor PECVD of being able to deposit films with tunable functionality by adjusting the plasma precursor ratio. Here, an allylamine/allyl alcohol plasma copolymerization system was used to modify two-dimensional (2D) and three-dimensional (3D) substrates for biomedical applications. Films with customizable and predictable nitrogen and oxygen content, as well as surface wettability, were deposited on both Si wafers and 3D polymer scaffolds across a range of copolymerization conditions. Additionally, the bioreactivity of plasma-modified materials was evaluated using both human dermal fibroblast and E coli attachment studies.

• 出版日期2015-12