Hydroethanolic extracts from different genotypes of acai (Euterpe oleracea) presented antioxidant potential and protected human neuron-like cells (SH-SY5Y)

作者：Marchioro Raupp Torma Priscila do Carmo; Brasil Allana Von Sulzback; Carvalho Ana Vania; Jablonski Andre; Rabelo Thallita Kelly; Fonseca Moreira Jose Claudio; Gelain Daniel Pens; Flores Simone Hickmann; Augusti Paula Rossini; Rios Alessandro de Oliveira

来源：Food Chemistry, 2017, 222: 94-104.

DOI：10.1016/j.foodchem.2016.12.006

• Anthocyanins
• Carotenoids
• Antioxidant activity
• Dichlorofluorescein-diacetate assay
• Reactive oxygen species
• Breeding program

Fruit breeding programs have resulted in bioactive compounds increase and health effects. Thus, this study aimed to evaluate the antioxidant activity and neuroprotective effects of the hydroethanolic extracts from six gal (Euterpe oleracea) genotypes using ABTS, deoxyribose, and glutathione oxidation assays, as well as, SH-SY5Y cells insulted with H2O2. L22P13 genotype showed the highest total content of anthocyanins, while L06P13 showed a high content of total carotenoids. However, the genotypes showed no difference in the antioxidant activity by ABTS and deoxyribose assays. The hydroethanolic extracts from different genotypes of acai showed a protective effect (13-62%) on SH-SY5Y cells insulted by H2O2 at a concentration of 50 mu g/mL by DCFH-DA assay. Except L04P16, no genotypes showed cytotoxicity in the SRB assay. These results indicate that gal genotypes have antioxidant effect against reactive species generated in SH-SY5Y cells, suggesting a neuroprotective effect of the hydroethanolic extracts from these fruits.

• 出版日期2017-5-1