A Mass-Sensitive Approach for the Detection of Anaesthetic Xenon

作者：Hayden Oliver; Latif Usman; Dickert Franz L^*

来源：Australian Journal of Chemistry, 2011, 64(12): 1628-1632.

DOI：10.1071/CH11267

Quartz crystal microbalances (QCMs) were utilized for the detection of the noble gas xenon (Xe) by combining them with different recognition layers such as permethylated calixarenes (tetramethyl-tert-butylcalix[4] arene (Cal4Me), hexamethyl-tert-butylcalix[6] arene (Cal6Me)), and polyurethanes, with covalently embedded Cal4OH (Poly4Cal), or Cal6OH (Poly6Cal). A third type of sensitive material is synthesized from polyacrylic acid (PAA) and polyvinyl alcohol (PVA) and utilized as a sensitive coating. The results demonstrate that the Cal4Me layer gives higher response towards Xe, while, by the use of a second uncoated QCM channel, the influence of ambient humidity could be nearly completely compensated by signal subtraction. Moreover, the Cal4Me sensor shows excellent reversibility and rapid response time, providing a potentially reliable way to determine Xe during anaesthesia.

• 出版日期2011