Directed Self-Assembly of Dipeptides to Form Ultrathin Hydrogel Membranes

作者:Johnson Eleanor K; Adams Dave J; Cameron Petra J*
来源:Journal of the American Chemical Society, 2010, 132(14): 5130-5136.
DOI:10.1021/ja909579p

摘要

The dipeptide amphiphile Fmoc-Leu-Gly-OH has been induced to self-assemble into thin surface-supported hydrogel gel films and gap-spanning hydrogel membranes. The thickness can be closely controlled, giving films/membranes from tens of nanometers to millimeters thick. SEM and TEM have confirmed that the dipeptides self-assemble to form fibers, with the membranes resembling a dense "mat" of entangled fibers. The films and membranes were stable once formed. The films could be reversibly dried and collapsed, then reswollen to regain the gel structure.

  • 出版日期2010-4-14