Antibacterial application of polyvinylalcohol-nanogold composite membranes

作者：Ramdayal; Balasubramanian K^*

来源：Colloids and Surfaces A: Physicochemical and Engineering Aspects , 2014, 455: 174-178.

DOI：10.1016/j.colsurfa.2014.04.050

• Gold nanoparticles
• Antibacterial
• Phyllanthus emblica
• PVA
• TEM
• Xigo

The present invention explores the antibacterial efficacy of ultra stable gold nanoparticles (GNPs), embedded polyvinyl alcohol (PVA) hybrid membranes. A green approach to synthesize the ultra stable GNP's using Phyllanthus ernblica (amla) extract was adapted. These GNP's were impregnated in PVA matrix to fabricate hybrid PVA-nanogold membranes by solvent casting technique. The facile green synthesis resulted in spherical gold nanoparticles with an average diameter of 2-4nm. The Xigo analysis suggested the ultra high stability of these nanoparticles for more than 6 months. The interaction of GNP's with PVA matrix was studied using FTIR and the surface topology was studied using AFM. Antibacterial efficacy of these hybrid membranes was assessed using disc diffusion method against Gram positive and Gram negative bacterial strains. The inhibitory effects of the hybrid membranes resulted in a zone of inhibition of 0.8-1.0 cm over a period of 24 h.

• 出版日期2014-8-5