科研之友
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摘要
Agranulocytosis is a life-threatening disorder characterised by a greatly decreased number of circulating neutrophils below 500/mu L. This article presents two cases of agranulocytosis in patients treated with pegylated interferon and ribavirin due to chronic hepatitis C. Interferon induced hyperthyroidism, which required the use of a tyreostatic. Anti-thyroid drugs (ATD) used to treat hyperthyroidism can cause agranulocytosis. The synergistic reaction of ATD and interferon on bone marrow cannot be excluded. (Pol J Endocrinol 2012; 63(1): 52-55)
- 出版日期2012-2
