Acid-mediated activation of modified ring-closing metathesis catalysts

作者：Kim Seyoung; Hwang Wonmi; Lim In Seon; Kim Sung Hye; Lee Sang gi^*; Kim B Moon

来源：Tetrahedron Letters, 2010, 51(4): 709-713.

DOI：10.1016/j.tetlet.2009.11.112

To improve the reactivity of Grubbs catalyst, novel ligands were designed and synthesized which possess nitrogen-containing heterocycles such as imidazole and pyridine. The modified catalysts were treated with a range of acids and the acid salt forms were used as catalysts for ring-closing metathesis (RCM) reactions. As a result, reactions employing the acid-modified catalysts showed considerable reactivity enhancement in RCM.

• 出版日期2010-1-27