A New 5(6 -> 7)abeo-sterol from the twigs of Podocarpus fleuryi

作者:Liu, Juan; Yang, Caiqiong; Zhang, Junjie; Wu, Jichun; Chen, Yegao*
来源:Natural Product Research, 2017, 31(2): 175-180.
DOI:10.1080/14786419.2016.1224870

摘要

A new 5(6 -> 7)abeo-sterol with rarely reported [6-5-6-5]-fused rings, 3 beta,5 beta,6-trihydroxyl-B-norsitostane (1), along with 10 known compounds were isolated from the twigs of Podocarpus fleuryi. Their structures were elucidated by means of extensive spectroscopic analysis. Compound 1 was assessed for their cytotoxicity against five human tumour cell lines (HL-60, SMMC-7721, A-549, MCF-7 and SW-480), and the result showed that it had no activity. [GRAPHICS] .