A comparative chemical-biological evaluation of titanium(IV) complexes with a salan or cyclopentadienyl ligand

作者:Schur Julia; Manna Cesar M; Deally Anthony; Koester Reinhard W; Tacke Matthias; Tshuva Edit Y; Ott Ingo*
来源:Chemical Communications, 2013, 49(42): 4785-4787.
DOI:10.1039/c3cc38604j

摘要

Titanium(IV) complexes with a salan or cyclopentadienyl ligand showed different biological behaviour concerning binding to biomolecules, cellular accumulation and intracellular distribution. Binding efficacy as well as trafficking on the cellular level are crucial parameters for their biological effects.