An ultrasensitive peroxidase DNAzyme-associated aptasensor that utilizes a target-triggered enzymatic signal amplification strategy

作者：Fu Rongzhan; Jeon Kyungeun; Jung Cheulhee; Park Hyun Gyu^*

来源：Chemical communications, 2011, 47(35): 9876-9878.

DOI：10.1039/c1cc13122b

By rationally employing enzymes for signal amplification, an ultrasensitive aptasensor was developed and successfully tested in a system designed to detect lysozyme with a detection limit of 0.1 fM. This detection limit is nearly three orders of magnitude lower than those of any previously reported DNAzyme-based aptasensors.

• 出版日期2011