A case of NDM-1-producing Acinetobacter baumannii transferred from India to Japan

作者：Nakazawa Yasushi^*; Ii Ryoko; Tamura Taku; Hoshina Tokio; Tamura Kumiko; Kawano Shinji; Kato Tetsuro; Sato Fumiya; Horino Tetsuya; Yoshida Masaki; Hori Seiji; Sanui Masamitsu; Ishii Yoshikazu; Tateda Kazuhiro

来源：Journal of Infection and Chemotherapy, 2013, 19(2): 330-332.

DOI：10.1007/s10156-012-0469-5

• Metallo-beta-lactamase
• Acinetobacter baumannii
• OXA-type carbapenemase

A 52-year-old male Japanese businessman with massive cerebral bleeding was transferred from India to Japan and was admitted to our hospital. Multidrug-resistant Acinetobacter baumannii was isolated from his sputum. The minimum inhibitory concentrations for this strain were as follows: imipenem, 64 mu g/ml; meropenem, 32 mu g/ml; ciprofloxacin, 16 mu g/ml; amikacin, 16 mu g/ml; aztreonam, 16 mu g/ml; colistin, %26lt; 1 mu g/ml. This A. baumannii strain had both bla (NDM-1) and bla (OXA-23) by polymerase chain reaction analysis. In Japan, NDM-1-producing bacteria are extremely rare in clinical specimens. To date, three NDM-1-positive cases have been detected in Japan, and this is the first case of A. baumannii-producing NDM-1 in Japan. Our case suggests that NDM-1-producing bacteria could be introduced into our country easily. There is concern that various resistant bacteria may be transferred from epidemic countries as a result of international medical care.

• 出版日期2013-4