Negative reward expectations in Borderline Personality Disorder patients: Neurophysiological evidence

作者：Vega Daniel; Soto Angel; Amengual Julia L; Ribas Joan; Torrubia Rafael; Rodriguez Fornells Antoni; Marco Pallares Josep^*

来源：Biological Psychology, 2013, 94(2): 388-396.

DOI：10.1016/j.biopsycho.2013.08.002

• Borderline Personality Disorder
• Feedback-Related Negativity
• Reward
• Error
• Theta oscillatory activity

Borderline Personality Disorder (BPD) patients present profound disturbances in affect regulation and impulse control which could reflect a dysfunction in reward-related processes. The current study investigated these processes in a sample of 18 BPD patients and 18 matched healthy controls, using an event-related brain potentials methodology. Results revealed a reduction in the amplitude of the Feedback-Related Negativity of BPD patients, which is a neurophysiological index of the impact of negative feedback in reward-related tasks. This reduction, in the effect of negative feedback in BPD patients, was accompanied by a different behavioral pattern of risk choice compared to healthy participants. These findings confirm a dysfunctional reward system in BDP patients, which might compromise their capacity to build positive expectations of future rewards and decision making.

• 出版日期2013-10