Phage-assisted assembly of organic inorganic hybrid bilayers

作者：Moghimian Pouya^*; Kilper Stefan; Srot Vesna; Rothenstein Dirk; Facey Sandra J; Hauer Bernhard; Bill Joachim; van Aken Peter A

来源：International Journal of Materials Research, 2016, 107(4): 295-299.

DOI：10.3139/146.111351

• M13 phage
• Biomineralization
• Hybrid nanostructures
• Organic inorganic multilayers
• Bioinspired materials

Protein-based bottom-up synthesis of functional nanomaterials and devices is one of the most promising areas in bio-nanotechnology. Here, we demonstrate that organic assemblies can serve as biologically controllable scaffolds for the deposition of inorganic nanoparticles. In this work, wild-type M13 phages were employed for controlled mineralization of zinc oxide particles. Our aim was to construct layered structures of organic and inorganic materials which contain alternating layers on a smooth substrate. The structure, elemental composition, and also the integrity of the organic and the biologically-templated inorganic layers were studied. A uniform nano-hybrid structure without significant thickness fluctuations was fabricated by using a high concentration of M13 phages and a carbon-coated substrate. The current study gives insight into the combination of organic inorganic materials to form a multilayered structure, which in turn sets the stage for the fabrication of electronic devices, e.g. actuators or capacitors.