Non-synonymous SNPs in MC1R gene are associated with the extended black variant in domestic ducks (Anas platyrhynchos)

作者：Yu, Wenhua; Wang, Cui; Xin, Qingwu; Li, Shijun; Feng, Yanping; Peng, Xiuli; Gong, Yanzhang^*

来源：Animal Genetics, 2013, 44(2): 214-216.

DOI：10.1111/j.1365-2052.2012.02377.x

• duck
• extended black
• melanocortin 1 receptor
• melanism
• plumage color

In this study, we performed a sequence characterization of the duck melanocortin 1 receptor (alpha-melanocyte stimulating hormone receptor) (MC1R) gene to analyze the relationship between MC1R polymorphism and the extended black variant in domestic ducks based on the extended black (E) and non-extended black (e+) allele hypothesis of the duck MC1R gene. Both c.52G>A and c.376G>A substitutions are highly associated with the duck extended black variant (P<0.01), but the novel c.52G>A substitution is more of a fit for the allele hypothesis of the duck MC1R gene.

• 出版日期2013-4
• 单位华中农业大学