Microwave assisted solvent free synthesis of alpha,alpha '-bis (arylidene) cycloalkanones by sulfated zirconia catalyzed cross aldol condensation of aromatic aldehydes and cycloalkanones

作者：Rawal Kirat; Mishra Manish Kumar^*; Dixit Manish; Srinivasarao Meka

来源：Journal of Industrial and Engineering Chemistry, 2012, 18(4): 1474-1481.

DOI：10.1016/j.jiec.2012.02.011

• Acid catalysis
• Bronsted acidity
• Cross aldol condensation
• Claisen Schmidt reaction
• Microwave irradiation
• Sulfated zirconia

The catalytic application of sulfated zirconia as solid Bronsted acid catalyst was explored for cross aldol condensation reactions (Claisen Schmidt reaction). The synthesized catalyst was highly active for solvent free synthesis of alpha,alpha '-bis(arylidene)cycloalkanones by cross aldol condensation of aromatic aldehydes with cycloalkanones. The microwave assisted synthesis resulted increased yields of the products (79-99%) at significantly lower reaction temperature (120-140 degrees C) and reaction time (20 min) as compared to the synthesis by thermal heating (63-96% yield at 170 degrees C after 4 h). The microwave irradiation afforded selectively cross aldol products. The catalyst could be easily regenerated and reused several times with similar efficiency.

• 出版日期2012-7-25