Association of Adolescent Obesity with Nonalcoholic Fatty Liver Disease and Related Risk Factors in Xi 'an, China

作者：Yan Rong; Niu Chun-Yan^*; Zhao Hong-Xin; Yu Lu; Wang Wen; Tian Yu

来源：Annals of Hepatology, 2018, 17(1): 85-91.

DOI：10.5604/01.3001.0010.7538

• Adolescents
• Obesity
• Nonalcoholic fatty liver disease
• Prevalence
• Risk factors

Introduction and aim. To investigate the association of adolescent obesity with nonalcoholic fatty liver disease (NAFLD) and related risk factors in Xi 'an, China. Material and methods. A total of 4141 adolescents (2,061 girls and 2,080 boys, mean age: 18.62 +/- 0.66 years, age range 15-22 years) were enrolled in this investigation. Anthropometric index was measured, and liver ultrasonography and liver function biochemical test were performed in all the subjects. T test, chi(2) test and logistic regression analysis were used for statistical analyses. Results. The total rates of obesity was 7.9% (08/4,141). The prevalence rate of NAFLD was 8.1% (335/4141) with a declining trend from obesity, overweight to normal BMI. NAFLD prevalence rate in obese boys was significantly higher than in girls (chi(2) = 56.5, P < 0.01). BMI, body weight, ALT, and AST in NAFLD group were higher than in non-NAFLD group (P < 0.05). The tangent point of ALT was 36 U/L using Youden index in boys, and 33 U/L in girls. Conclusion. The prevalence of obesity and NAFLD in adolescents is higher in Xi'an than anticipated. Body weight and BMI may be the associated independent risk factors of NAFLD.

• 出版日期2018-2
• 单位西安医学院; 河南省人民医院