Amperometric nonenzymatic determination of glucose via a glassy carbon electrode modified with nickel hydroxide and N-doped reduced graphene oxide

作者：Zhang, Yuehua; Lei, Wu^*; Wu, Qiuju; Xia, Xifeng; Hao, Qingli^*

来源：Microchimica Acta, 2017, 184(9): 3103-3111.

DOI：10.1007/s00604-017-2332-y

• Electrocatalysis
• Amperometric determination
• Cyclic voltammetry
• Glucose
• Nickel hydroxide
• Nanomaterial
• Nonenzymatic sensor

The authors describe a nonenzymatic glucose sensor that was obtained by electrochemical deposition and oxidization of metallic nickel on the surface of nitrogen-doped reduced graphene oxide (N-RGO) placed on a glassy carbon electrode (GCE). An analysis of the morphology and chemical structure indicated the composite to possess a well-defined vermicular Ni(OH)(2) nanorods combined with N-RGO. The electrochemical performance of the modified GCE with respect to the detection of glucose in 0.1 M NaOH was investigated by cyclic voltammetry and amperometry. The wrinkle and protuberance of N-RGO for loading of nanostructured Ni(OH)(2) are found to increase electrical conductivity, surface area, electrocatalytical activity and stability. The modified GCE displays a high electrocatalytic activity towards the oxidation of glucose in 0.1 M NaOH solution. The lower detection limit is 0.12 mu M at an applied potential of +0.45 V (vs Ag/AgCl) (S/N=3), and the sensitivity is 3214 mu A mM(-1) cm(-2). The modified GCE possesses long-term stability, good reproducibility and high selectivity over fructose, sucrose and lactose.

• 出版日期2017-9
• 单位南京理工大学