Does proteolysis explain glutamine release from the septic brain?

作者:Dejong Cornelius H C*; Damink Steven W M Olde
来源:Critical Care, 2010, 14(3): 152.
DOI:10.1186/cc8971

摘要

Berg and colleagues report on amino acid exchange across the human brain during endotoxin infusion. Lipopolysaccharide infusion induced a decrease in the ratio between branched chain amino acids and aromatic amino acids, increased unidirectional phenylalanine uptake, and increased net brain glutamine release. Cerebral proteolysis is suggested to play a role, but the question is whether this is the case and why this would happen.

  • 出版日期2010

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