A facile, three-component domino protocol for the microwave-assisted synthesis of functionalized naphtho[2,3-b]furan-4,9-diones in water

作者：Prasanna Pitchaimani^*; Balamurugan Kamaraj; Perumal Subbu; Carlos Menendez J

来源：Green Chemistry, 2011, 13(8): 2123-2129.

DOI：10.1039/c0gc00952k

A three-component domino reaction of 2-hydroxy-1,4-naphthoquinone, aromatic aldehydes and a pyridinium salt in the presence of ammonium acetate, under microwave irradiation and using water as solvent, furnished a library of novel 2-arylcarbonyl-3-aryl-4,9-dihydronaphtho-[2,3-b]furan-4,9-diones in good yields, in a transformation that presumably proceeds via an alpha,beta-unsaturated triketone generation/Michael addition/intramolecular cyclisation/air oxidation one-pot sequence.

• 出版日期2011