Acute unilateral peripheral vestibulopathy in neurosyphilis

作者：Young Allison S^*; Carroll Antonia S; Welgampola Miriam S; McCluskey Peter J; van Hal Sebastian J; Thompson Elizabeth O; Burn Juliet; Fulham Michael J; Halmagyi G Michael

来源：Journal of the Neurological Sciences, 2017, 378: 55-58.

DOI：10.1016/j.jns.2017.04.038

• Neurosyphilis
• Acute unilateral peripheral vestibulopathy
• Basal meningitis
• Cranial nerve palsy

Introduction: Neurosyphilis producing basal meningitis presenting as sequential transient cranial nerve palsies was well recognized before the antibiotic era.
Objective: To report two patients presenting with acute unilateral peripheral vestibulopathy due to syphilitic basal meningitis.
Results: In Case 1 basal meningitis occurred early in the secondary phase of the infection, in Case 2 in the late latent phase. The diagnosis was not made immediately in either case; in Case 1 after previous presentation with increasing hearing loss and then with facial palsy and then a subsequent presentation with optic neuritis; in Case 2 after investigation for possible lymphoma.
Conclusion: Syphilitic basal meningitis in either the secondary or in the latent phase can present as acute unilateral peripheral vestibulopathy with transient involvement of the facial or auditory nerve.

• 出版日期2017-7-15