Atopic dermatitis: emerging therapies

作者:Simpson Eric*; Udkoff Jeremy; Borok Jenna; Tom Wynnis; Beck Lisa; Eichenfield Lawrence F
来源:Seminars in Cutaneous Medicine and Surgery, 2017, 36(3): 124-130.
DOI:10.12788/j.sder.2017.0137

摘要

Crisaborole and dupilumab represent the first 2 Food and Drug Administration (FDA)-approved therapies for atopic dermatitis (AD) in more than 15 years, and there are many promising drugs currently in development. This new wave of therapeutics capitalizes on the large body of work clarifying the pathogenesis of AD over the last several decades. In particular, type 2 cytokine-driven inflammation and skin barrier dysfunction are key processes underlying AD pathogenesis.

  • 出版日期2017-9