Non-volumetric echocardiographic indices and qualitative assessment of right ventricular systolic function in Ebstein's anomaly: comparison with CMR-derived ejection fraction in 49 patients

作者：Kuehn Andreas; Meierhofer Christian; Rutz Tobias; Rondak Ina Christine; Roehlig Christoph; Schreiber Christian; Fratz Sohrab; Ewert Peter; Vogt Manfred^*

来源：European Heart Journal-Cardiovascular Imaging, 2016, 17(8): 930-935.

DOI：10.1093/ehjci/jev243

• Ebstein's anomaly
• echocardiography
• cardiovascular magnetic resonance
• right ventricular function

Aims Ebstein's anomaly (EA) is often associated with right ventricular (RV) dysfunction. Data on echocardiographic quantification of RV function are, however, rare. The aim of this study was to determine how non-volumetric echocardiographic indices and qualitative assessment of global systolic RV function correlate with cardiovascular magnetic resonance (CMR)-derived RV ejection fraction (EF).
Methods and results We compared six echocardiographic indices and qualitative assessment of RV function with the gold standard CMR. A total of 49 unoperated patients with EA and a mean age of 32 +/- 18 years were examined. Tricuspid annular plane systolic excursion, tissue Doppler myocardial velocities (peak S and IVA) and 2D strain and strain rate measures for the RV were compared with CMR-derived EF. Only 2D global longitudinal strain (2D-GLS), out of the six parameters investigated, showed a weak, although statistically significant correlation with CMR-derived RVEF (R = -0.4, P = 0.01). Using a cut-off value of -20.15, 2D-GLS sensitivity (77%) and specificity (46%) in detecting patients with a CMR-derived EF of,<50% were comparable with qualitative assessment (sensitivity 77%, specificity 45%).
Conclusion Overall echocardiographic parameters of RV function correlate poorly with CMR-derived EF in patients with EA. Only 2D global longitudinal RV strain correlated weakly with CMR-derived RVEF. However, the sensitivity and specificity for detecting RV dysfunction using 2D strain imaging were comparable with qualitative RV functional assessment.

• 出版日期2016-8-1
• 单位河北医科大学