Application of radiopaque micro-particle fillers for 3-D imaging of periodontal pocket analogues using cone beam CT

作者：Elashiry M^*; Meghil M M; Kalathingal S; Buchanan A; Elrefai R; Looney S; Rajendran M; Ochieng M; Young N; Elawady A; Arce R M; Sandhage K H; Cutler C W

来源：Dental Materials, 2018, 34(4): 619-628.

DOI：10.1016/j.dental.2018.01.008

Background. Periodontitis is an infectious/inflammatory disease most often diagnosed by deepening of the gingival sulcus, which leads to periodontal pockets (PPs) conventional manual periodontal probing does not provide detailed information on the three-dimensional (3-D) nature of PPs.
Objectives. To determine whether accurate 3-D analyses of the depths and volumes of calibrated PP analogues (PPAs) can be obtained by conventional cone beam computed tomography (CBCT) coupled with novel radiopaque micro-particle fillers (described in the companion paper) injected into the PPAs.
Methods. Two PPA models were employed: (1) a human skull model with artificial gingiva applied to teeth with alveolar bone loss and calibrated PPAs, and (2) a pig jaw model with alveolar bone loss and surgically-induced PPAs The PPAs were filled with controlled amounts of radiopaque micro-particle filler using volumetric pipetting Inter-method and intra-method agreement tests were then used to compare the PPA depths and volumes obtained from CBCT images with values obtained by masked examiners using calibrated manual methods.
Results. Significant inter-method agreement (0.938-0.991) and intra-method agreement (0.94-0.99) were obtained when comparing analog manual data to digital CBCT measurements enabled by the radiopaque filler. Published by Elsevier Ltd on behalf of The Academy of Dental Materials.

• 出版日期2018-4