Asymmetric tandem reactions of N-sulfonylimines and α,β-unsaturated aldehydes: an alternative reaction pathway to that of using saturated aldehydes

作者：An, Qianjin; Li, Jing; Shen, Jiefeng; Butt, Nicholas; Liu, Delong^*; Liu, Yangang; Zhang, Wanbin

来源：Chemical communications, 2015, 51(5): 885-888.

DOI：10.1039/c4cc07051h

• ORGANOCATALYTIC DOMINO REACTIONS
• DIELS-ALDER REACTIONS
• CYCLIC KETIMINES
• DIASTEREOSELECTIVE SYNTHESIS
• STEREOSELECTIVE-SYNTHESIS
• TRANSFER HYDROGENATION
• MICHAEL ADDITION
• PIPERIDINES
• ACIDS
• STEREOCENTERS

An organocatalyzed asymmetric tandem reaction of cyclic N-sulfonylimines and alpha,beta-unsaturated aldehydes was developed. These substrates follow an alternative reaction pathway to that of reactions involving saturated aldehydes, affording similar piperidine derivatives.

• 出版日期2015
• 单位上海交通大学