Microfluidic integration of photonic crystal fibers for online photochemical reaction analysis

作者:Unterkofler S*; McQuitty R J; Euser T G; Farrer N J; Sadler P J; Russell P St J
来源:Optics Letters, 2012, 37(11): 1952-1954.
DOI:10.1364/OL.37.001952

摘要

Liquid-filled hollow-core photonic crystal fibers (HC-PCFs) are perfect optofluidic channels, uniquely providing low-loss optical guidance in a liquid medium. As a result, the overlap of the dissolved specimen and the intense light field in the micronsized core is increased manyfold compared to conventional bioanalytical techniques, facilitating highly-efficient photoactivation processes. Here we introduce a novel integrated analytical technology for photochemistry by microfluidic coupling of a HC-PCF nanoflow reactor to supplementary detection devices. Applying a continuous flow through the fiber, we deliver photochemical reaction products to a mass spectrometer in an online and hence rapid fashion, which is highly advantageous over conventional cuvette-based approaches.

  • 出版日期2012-6-1