A prototypical interface for deep brain stimulation

作者：Shen Ding Lan^*; Chen Hong Wen

来源：MICROELECTRONICS JOURNAL, 2014, 45(1): 119-125.

DOI：10.1016/j.mejo.2013.10.009

• Deep brain stimulation
• Transconductance amplifier
• Biphasic current
• Switched op-amp
• Capacitor DAC

This paper presents a prototypical interface circuit for deep brain stimulation surgery. It provides four channel outputs with a stimulating current. This stimulating circuit adjusts its output current by utilizing the switched-capacitor DAC and voltage-to-current transconductance amplifiers with the power-down mode to achieve a higher resolution and to save the power dissipation. The biphasic stimulating waveform is generated using a bridge switching technique and the programmable pulse signals are adjustable for width and frequency. By fabricating with a standard 0.35-mu m CMOS technology at a 3.3 V supply voltage, the reduced output stimulating current has 8-bit resolutions for amplitudes between 5 mu A and 155 mu A, 4-bit resolutions for frequencies between 126 Hz and 244 Hz, and 4-bit resolutions for time intervals between 0 mu s and 120 mu s.

• 出版日期2014-1