A new prenylated aurone from Artocarpus altilis

作者：Tran Thu Huong; Nguyen Xuan Cuong^*; Le Huyen Tram; Tran Thuong Quang; Le Van Duong; Nguyen Hoai Nam; Nguyen Tien Dat; Phan Thi Thanh Huong; Chau Ngoc Diep; Phan Van Kiem; Chau Van Minh

来源：Journal of Asian Natural Products Research, 2012, 14(9): 923-928.

DOI：10.1080/10286020.2012.702758

• Artocarpus altilis
• Moraceae
• prenylated aurone
• artocarpaurone
• antioxidant

Phytochemical study of the methanol extract of Artocarpus altilis resulted in the isolation of a new prenylated aurone, artocarpaurone (1), together with eight known compounds including two prenylated chalcones (2 and 3), three prenylated flavanones (4-6), and three triterpenes (7-9). The structure of 1 was elucidated as 6-hydroxy-2-[8-hydroxy-2-methyl-2-(4-methyl-3-pentenyl)-2H-1-benzopyran-5-ylmethylene]-3(2H)-benzofuranone by spectroscopic methods including 1D and 2D NMR spectra and FT-ICR-MS. Compound 1 showed moderate nitric oxide radical scavenging activity, whereas 2 and 3 had moderate 2,2-diphenyl-1-picrylhydrazyl radical scavenging effect, compared with the positive control (+)-catechin.

• 出版日期2012
• 单位华中科技大学