Are all forms of feature binding disturbed in schizophrenia? Evidence from a central vs. peripheral distinction in working memory

作者：Altamura Mario^*; Padalino Flavia A; Mammarella Nicola; Fairfield Beth; Balzotti Angela; Di Domenico Alberto; Frisullo Elisa; Bellomo Antonello

来源：Psychiatry Research, 2013, 209(1): 9-14.

DOI：10.1016/j.psychres.2012.11.015

• Peripheral feature binding
• Context memory
• Episodic buffer system
• Episodic memory

In this study we investigated central and peripheral feature binding in a group of 24 high pre-morbid IQ patients with schizophrenia and 24 healthy controls. In particular, participants were asked to remember specific single (e.g., word, colour) or multiple features (e.g., coloured words) of experimental items with central (coloured word) vs. peripheral (a coloured frame) attributes in a working memory binding task. Performance of the patients was significantly inferior to that of controls, especially when required to remember the peripheral combination of multiple features. Results suggest that patients with schizophrenia may have difficulties in unitizing peripheral features in working memory.

• 出版日期2013-8-30