Use of string test and stool specimens to diagnose pulmonary tuberculosis

作者：DiNardo Andrew R^*; Hahn Andrew; Leyden Jacinta; Stager Charles; Baron Ellen Jo; Graviss Edward A; Mandalakas Anna M; Guy Elizabeth

来源：International Journal of Infectious Diseases, 2015, 41: 50-52.

DOI：10.1016/j.ijid.2015.10.022

• Tuberculosis
• String test
• Stool
• Xpert MTB/RIF

Background: The Xpert MTB/RIF (MTB/RIF) test has advanced the field of tuberculosis (TB) diagnostics; however, depending on age and HIV status, 10-85% of individuals with presumed pulmonary TB (PTB) are unable to produce sputum.
Methods: The feasibility of using MTB/RIF and culture on stool and string test specimens from 13 adult patients with presumed PTB was studied.
Results: The string test was well tolerated with a median Wong Baker Faces score of 2. The string test had 100% sensitivity and specificity by MTB/RIF and 87.5% sensitivity and 100% specificity by culture. In stool, Mycobacterium tuberculosis DNA was detected in all cases of culture-confirmed PTB.
Conclusion: The string test and stool provide diagnostic specimens that warrant further investigation.

• 出版日期2015-12