An evolutionary approach for biclustering of gene expression data

作者：Sheta Walaa^*; Hany Maha; Mahdi Shereef

来源：International Journal of Bio-Inspired Computation, 2010, 2(6): 413-421.

DOI：10.1504/IJBIC.2010.037021

• biclustering
• gene expression data
• bioinformatics evolutionary computation

This paper presents an evolutionary algorithm for analysing the patterns of gene expression on microarray data. Microarray technologies have provided the means to monitor the expression levels of a large number of genes simultaneously. Gene clustering is important in analysing a large body of microarray expression data. The proposed method simultaneously solves gene clustering problems. The proposed algorithm was tested on yeast microarray dataset. The experimental clustering and visual results indicate that the proposed algorithm grouped genes with similar gene expressions. These results indicate that the proposed algorithm has potential in analysing gene expression patterns.

• 出版日期2010