Amyotrophic lateral sclerosis and ocular flutter

作者:Balaratnam Michelle S; Leschziner Guy D; Seemungal Barry M; Bronstein Adolfo M; Guiloff Roberto J*
来源:Amyotrophic Lateral Sclerosis, 2010, 11(3): 331-334.
DOI:10.3109/17482960902875133

摘要

A previously unreported association of amyotrophic lateral sclerosis and ocular flutter is presented. It is hypothesized that initial loss of brainstem inhibitory interneurons resulted in disinhibition of burst interneurons and that the ocular flutter subsequently disappeared as burst interneurons also became affected by the disease process. The association adds clinical evidence of involvement of brainstem interneurons to other evidence of involvement of neurons other than motor neurons in the disease process.

  • 出版日期2010-5